Concepedia

LAPTM4B: A novel cancer-associated gene motivates multidrug resistance through efflux and activating PI3K/AKT signaling

Li Li, Yan Pan, H C Li, Han Yang, Qun He, Yanli Pang, Yi Shan, Fuxia Xiong, Genze Shao, Ruixin Zhou

Oncogene · 2010 · 122 citations · 27 references

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27

HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells

Christiane Knuefermann, Yang Lü, Bolin Liu et al. · Oncogene · 2003 · 454 citations

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Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NFκB pathway

Byeong Hyeok Choi, Chang Gun Kim, Yoongho Lim et al. · Cancer Letters · 2007 · 217 citations

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Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts

Pier Luigi Tazzari, A Cappellini, Francesca Ricci et al. · Leukemia · 2007 · 199 citations

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Molecular cloning and characterization of LAPTM4B, a novel gene upregulated in hepatocellular carcinoma

Genze Shao, Rouli Zhou, Qingyun Zhang et al. · Oncogene · 2003 · 165 citations

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Phosphatidylinositol 3′-Kinase Activation Leads to Multidrug Resistance Protein-1 Expression and Subsequent Chemoresistance in Advanced Prostate Cancer Cells

John Tayu Lee, Linda S. Steelman, James A. McCubrey · Cancer Research · 2004 · 157 citations

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