Binding studies of taxanes to human serum albumin by bioaffinity chromatography and circular dichroism

The Characterization of Two Specific Drug Binding Sites on Human Serum Albumin

Gillian Sudlow, D. J. Birkett, D. N. Wade · Molecular Pharmacology · 1975 · 1.7K citations

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Alex Sparreboom, Judith van Asperen, Ulrich Mayer et al. · Proceedings of the National Academy of Sciences · 1997 · 877 citations · Full text

Active Epithelial Excretion, Gastrointestinal Pharmacology, Immunology +16

Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel.

Nuhad K. Ibrahim, Neil Desai, Sewa S. Legha et al. · PubMed · 2002 · 630 citations

Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients.

Simona Mozzetti, Cristiano Ferlini, Paola Concolino et al. · PubMed · 2005 · 327 citations

Endocrine-related Cancer, Medicine, Paclitaxel Resistance +15

Class III β-Tubulin Overexpression Is a Prominent Mechanism of Paclitaxel Resistance in Ovarian Cancer Patients

Simona Mozzetti, Cristiano Ferlini, Paola Concolino et al. · Clinical Cancer Research · 2005 · 295 citations · Full text

Oncology, Medicine, Paclitaxel Resistance +14