Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel. - Concepedia

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Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel.

630

Citations

18

References

2002

Year

Nuhad K. Ibrahim, Neil Desai, Sewa S. Legha, Patrick Soon‐Shiong, Richard L. Theriault, Edgardo Rivera, Bita Esmaeli, Sigrid Ring, Agop Y. Bedikian, Gabriel N. Hortobágyi,

Abstract

ABI-007 offers several features of clinical interest, including rapid infusion rate, absence of requirement for premedication, and a high paclitaxel MTD. Our results provide support for Phase II trials to determine the antitumor activity of this drug.

References

	Year	Citations

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