Comparative study of anti-inflammatory and ulcerogenic activities of different cyclo-oxygenase inhibitors

Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors:  Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1<i>H</i>-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)

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Pharmacy, Medicinal Chemistry, Pharmacology +17

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.

Karen Seibert, Y Zhang, K. Leahy et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations

Medicine, Pharmacology, Pharmacotherapy +17

Rofecoxib [Vioxx, MK-0966; 4-(4′-Methylsulfonylphenyl)-3-phenyl-2-(5 H)-furanone]: A Potent and Orally Active Cyclooxygenase-2 Inhibitor. Pharmacological and Biochemical Profiles

Chi‐Chung Chan, S. Boyce, Christine Brideau et al. · Journal of Pharmacology and Experimental Therapeutics · 1999 · 399 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +15

Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model

Elliot Ehrich, A. Dallob, I Delepeleire et al. · Clinical Pharmacology & Therapeutics · 1999 · 326 citations

Medicine, Pharmacology, Pharmacotherapy +16

Salicylates inhibit I kappa B-α phosphorylation, endothelial-leukocyte adhesion molecule expression, and neutrophil transmigration

Jacqueline W. Pierce, Margaret Read, Han Ting Ding et al. · The Journal of Immunology · 1996 · 302 citations · Full text

Life Sciences, Immunology, Pharmacology +17