Concepedia

Induction of G2/M phase arrest and apoptosis by a novel enediyne derivative, THDB, in chronic myeloid leukemia (HL-60) cells

Yu‐Jhang Lu, Sheng‐Huei Yang, Ching‐Ming Chien, Yi‐Hsiung Lin, Xiu‐Wei Hu, Zchong‐Zcho Wu, Ming‐Jung Wu, Shinne‐Ren Lin

Toxicology in Vitro · 2006 · 39 citations · 16 references

DOI

Concepts

References

16

Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells.

Laurence Gamet‐Payrastre, Pengfei Li, Solange Lumeau et al. · PubMed · 2000 · 619 citations

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Mechanisms of Taxol-induced cell death are concentration dependent.

Keila E. Torres, Susan Band Horwitz · PubMed · 1998 · 389 citations

, , +17

Inhibition of p34cdc2 kinase activity by etoposide or irradiation as a mechanism of G2 arrest in Chinese hamster ovary cells.

Richard B. Lock, Warren E. Ross · PubMed · 1990 · 219 citations

, , +12

G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.

P M O'Connor, Douglas K. Ferris, Michele Pagano et al. · Journal of Biological Chemistry · 1993 · 161 citations · Full text

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Persistent DNA damage inhibits S-phase and G2 progression, and results in apoptosis.

David K. Orren, Lone Nørgård Pétersen, Vilhelm A. Bohr · Molecular Biology of the Cell · 1997 · 139 citations

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