Richard B. Lock

Monoclonal Antibody-Mediated Targeting of CD123, IL-3 Receptor α Chain, Eliminates Human Acute Myeloid Leukemic Stem Cells

Liqing Jin, Erwin M. Lee, Hayley S. Ramshaw et al. · Cell stem cell · 2009 · 523 citations · Full text

Medicine, Hematology, Oncology +14

The pediatric preclinical testing program: Description of models and early testing results

Peter J. Houghton, Christopher L. Morton, Chandra L. Tucker et al. · Pediatric Blood & Cancer · 2006 · 483 citations

Medicine, Oncology, Cancer Pharmacology +14

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

Andrei V. Krivtsov, Kathryn Evans, Jayant Y. Gadrey et al. · Cancer Cell · 2019 · 449 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +14

Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer

Marie Wong, Chelsea Mayoh, Loretta M. S. Lau et al. · Nature Medicine · 2020 · 404 citations · Full text

Life Sciences, Genetics, Oncology +14

Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells

Kathleen M. Murphy, Velvizhi Ranganathan, M L Farnsworth et al. · Cell Death and Differentiation · 2000 · 358 citations

Life Sciences, Cell Biology, Pharmacology +16