Richard B. Lock

Monoclonal Antibody-Mediated Targeting of CD123, IL-3 Receptor α Chain, Eliminates Human Acute Myeloid Leukemic Stem Cells

Liqing Jin, Erwin M. Lee, Hayley S. Ramshaw et al. · Cell stem cell · 2009 · 523 citations · Full text

Hematological Malignancy, Cell Therapy, Immune Cell Development +10

The pediatric preclinical testing program: Description of models and early testing results

Peter J. Houghton, Christopher L. Morton, Chandra L. Tucker et al. · Pediatric Blood & Cancer · 2006 · 482 citations

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

Andrei V. Krivtsov, Kathryn Evans, Jayant Y. Gadrey et al. · Cancer Cell · 2019 · 421 citations · Full text

Hematological Malignancy, Chromatin, Mll-rearranged Leukemia +9

Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer

Marie Wong, Chelsea Mayoh, Loretta M. S. Lau et al. · Nature Medicine · 2020 · 372 citations

Functional Genomics, High-risk Pediatric Cancer, Medicine +9

Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells

Kathleen M. Murphy, Velvizhi Ranganathan, M L Farnsworth et al. · Cell Death and Differentiation · 2000 · 356 citations · Full text

Tumor Biology, Human Tumor Cells, Mitochondrial Function +9