BMJ · 1979 · 152 citations · 13 references
MedicineNutritionSurgeryClinical NutritionGastroenterologyHuman NutritionDietary ManagementGastrointestinal DiseaseInflammatory Bowel DiseaseIntestinal ObstructionNutrition In Gastrointestinal DisordersNutritional GastroenterologyInflammatory Bowel Disease Diet TherapyInflammatory Bowel Disease Nutrition TherapyInflammatory Bowel Disease Surgery NutritionInflammatory Bowel Disease TherapyIntestinal Obstruction SurgeryLarge Intestinal ObstructionMatched StudiesNutrition In Crohn's Disease
Thirty-two patients with Crohn's disease were treated with a fibre-rich, unrefined-carbohydrate diet in addition to conventional management and followed for a mean of four years and four months. Their clinical course was compared retrospectively with that of 32 matched patients who had received no dietary instruction. Hospital admissions were significantly fewer and shorter in the diet-treated patients, who spent a total of 111 days in hospital compared with 533 days in the non-diet-treated control group. Whereas five of the controls required intestinal operation, only one diet-treated patient needed surgery. This is in strong contrast to general experience with this disease. Treatment with a fibre-rich, unrefined-carbohydrate diet appears to have a favourable effect on the course of Crohn's disease and does not lead to intestinal obstruction.
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Annals of Internal Medicine · 1979 · 323 citations
Refined Carbohydrate Foods and Disease
Ivan M. Sharman · BMJ · 1976 · 183 citations · Full text
Course and prognosis of Crohn's disease.
S. C. Truelove, A. S. Peña · Gut · 1976 · 176 citations · Full text