Expression of the human MGMT O6-methylguanine DNA methyltransferase gene in a yeast alkylation-sensitive mutant: its effects on both exogenous and endogenous DNA alkylation damage

Transformation of intact yeast cells treated with alkali cations

Hisao Ito, Y Fukuda, Kousaku Murata et al. · Journal of Bacteriology · 1983 · 7.7K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +10

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

Richard Fishel, Mary Kay Lescoe, Manchanahalli R. Satyanarayana Rao et al. · Cell · 1993 · 2.9K citations

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Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

Fredrick S. Leach, Nicholas C. Nicolaides, Nickolas Papadopoulos et al. · Cell · 1993 · 2.3K citations

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Mutator phenotype may be required for multistage carcinogenesis.

L A Loeb · PubMed · 1991 · 1.3K citations

Medicine, Genetics, Molecular Genetics +11

Hypermutability and mismatch repair deficiency in RER+ tumor cells

Ramon Parsons, Guo‐Min Li, Matthew J. Longley et al. · Cell · 1993 · 1.1K citations

Life Sciences, Genetics, Oncology +17