Use of solid supported nucleophiles and electrophiles for the purification of non-peptide small molecule libraries

Organic Chemistry on Solid Supports

Jörg S. Früchtel, Günther Jung · Angewandte Chemie International Edition in English · 1996 · 648 citations

Natural Sciences, Chemistry, Combinatorial Chemistry +14

Postcondensation Modifications of Ugi Four-Component Condensation Products:  1-Isocyanocyclohexene as a Convertible Isocyanide. Mechanism of Conversion, Synthesis of Diverse Structures, and Demonstration of Resin Capture

Thomas A. Keating, Robert W. Armstrong · Journal of the American Chemical Society · 1996 · 288 citations

Natural Sciences, Biochemistry, Chemistry +12

Solid-phase synthesis of oligosaccharides. I. Preparation of the solid support. Poly[p-(1-propen-3-ol-1-yl)styrene]

Conrad Schuerch, Jean M. J. Fréchet · Journal of the American Chemical Society · 1971 · 284 citations

Natural Sciences, Biochemistry, Chemistry +10

Strategy and Tactics in Combinatorial Organic Synthesis. Applications to Drug Discovery

Eric M. Gordon, Mark A. Gallop, Dinesh V. Patel · Accounts of Chemical Research · 1996 · 267 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +6

Activation Method to Prepare a Highly Reactive Acylsulfonamide “Safety-Catch” Linker for Solid-Phase Synthesis¹

Bradley J. Backes, Alex A. Virgilio, Jonathan A. Ellman · Journal of the American Chemical Society · 1996 · 253 citations

Natural Sciences, Chemistry, Physical Chemistry +6