Identification of a mutation in ADD1/SREBP-1 in the spontaneously hypertensive rat

Role of Fatty Acids in the Pathogenesis of Insulin Resistance and NIDDM

Guenther Boden · Diabetes · 1997 · 1.6K citations

Life Sciences, Endocrinology, Nutritional Sciences +14

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

Hitoshi Shimano, Jay D. Horton, Iichiro Shimomura et al. · Journal of Clinical Investigation · 1997 · 834 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

Iichiro Shimomura, Yuriy K. Bashmakov, Shinji Ikemoto et al. · Proceedings of the National Academy of Sciences · 1999 · 791 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +12

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells.

Iichiro Shimomura, Hitoshi Shimano, Jay D. Horton et al. · Journal of Clinical Investigation · 1997 · 754 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +11

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

Marc Foretz, C Guichard, Pascal Ferré et al. · Proceedings of the National Academy of Sciences · 1999 · 735 citations

Life Sciences, Biochemistry, Molecular Biology +16