LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas

Somatic mutations affect key pathways in lung adenocarcinoma

Li Ding, Gad Getz, David A. Wheeler et al. · Nature · 2008 · 2.7K citations · Full text

Medicine, Genetics, Oncology +16

Characterizing the cancer genome in lung adenocarcinoma

Barbara A. Weir, Michele Sue‐Ann Woo, Gad Getz et al. · Nature · 2007 · 1.1K citations · Full text

Medicine, Genetics, Oncology +17

LKB1 modulates lung cancer differentiation and metastasis

Hongbin Ji, Matthew R. Ramsey, D. Neil Hayes et al. · Nature · 2007 · 1.1K citations

Medicine, Cancer Biology, Oncology +11

Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung.

Montse Sánchez‐Céspedes, Paola Parrella, Manel Esteller et al. · PubMed · 2002 · 639 citations

Medicine, Genetics, Oncology +17

DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells

David J. Steger, Martina I. Lefterova, Aaron J. Stonestrom et al. · Molecular and Cellular Biology · 2008 · 524 citations · Full text

Life Sciences, Genetics, Molecular Biology +11