Cyclooxygenase Inhibitors Induce the Expression of the Tumor Suppressor Gene EGR-1, Which Results in the Up-Regulation of NAG-1, an Antitumorigenic Protein

Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells

Masahiko Tsujii, Sunao Kawano, Shingo Tsuji et al. · Cell · 1998 · 2.3K citations · Full text

Angiogenesis, Colon Cancer Cells, Medicine +4

MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-β superfamily

Michelle Bootcov, Asne R. Bauskin, Stella M. Valenzuela et al. · Proceedings of the National Academy of Sciences · 1997 · 1.1K citations · Full text

Macrophage Activation, Immunology, Pathology +17

Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing

Michael K. Jones, Hongtao Wang, B. M. Peskar et al. · Nature Medicine · 1999 · 821 citations

Inflammation, Nonsteroidal Anti-inflammatory Drugs, Ulcer Healing +12

The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling

Thierry Virolle, Eileen D. Adamson, Véronique Baron et al. · Nature Cell Biology · 2001 · 392 citations

Transcriptional Regulation, Signal Transduction, Signaling Pathway +8

Cyclooxygenase Inhibitors Regulate the Expression of a TGF-β Superfamily Member That Has Proapoptotic and Antitumorigenic Activities

Seung Joon Baek, Kyung Soo Kim, Jennifer B. Nixon et al. · Molecular Pharmacology · 2001 · 387 citations · Full text