Effect of peripheral administration of leptin on the renal sympathetic nerve activity in high-fat diet-related hypertensive rats

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene

Jeffrey L. Halaas, K.S. Gajiwala, Margherita Maffei et al. · Science · 1995 · 4.5K citations

Medicine, Endocrinology, Nutritional Sciences +17

Leptin enters the brain by a saturable system independent of insulin

William A. Banks, Abba J. Kastin, Wei Tao Huang et al. · Peptides · 1996 · 1.2K citations

Life Sciences, Endocrinology, Physiology +8

Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

Jeffrey L. Halaas, Carol N. Boozer, J. R. Blair‐West et al. · Proceedings of the National Academy of Sciences · 1997 · 1K citations

Medicine, Endocrinology, Physiology +17

Receptor-mediated regional sympathetic nerve activation by leptin.

William G. Haynes, Donald A. Morgan, Sarah Walsh et al. · Journal of Clinical Investigation · 1997 · 980 citations · Full text

Life Sciences, Endocrinology, Physiology +16