Concepedia

Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice

Tao Yu, Chunhong Liu, Pavel V. Belichenko, Steven J. Clapcote, Shaomin Li, Annie Pao, Alexander M. Kleschevnikov, Allison R. Bechard, Suhail Asrar, Rongqing Chen,

Brain Research · 2010 · 134 citations · 50 references

DOI

Concepts

References

50

A mouse model for Down syndrome exhibits learning and behaviour deficits

Roger H. Reeves, Nicholas G. Irving, Timothy H. Moran et al. · Nature Genetics · 1995 · 914 citations

, , +12

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21

Joseph R. Arron, Monte M. Winslow, Alberto Polleri et al. · Nature · 2006 · 698 citations

, , +11

Abnormal Spine Morphology and Enhanced LTP in LIMK-1 Knockout Mice

Yanghong Meng, Yu Zhang, Vitali Tregoubov et al. · Neuron · 2002 · 687 citations · Full text

, , +12

Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP

Youming Lu, Zhengping Jia, Christopher Janus et al. · Journal of Neuroscience · 1997 · 630 citations · Full text

, , +17

The Neuropsychology of Down Syndrome: Evidence for Hippocampal Dysfunction

Bruce F. Pennington, Jennifer Cregan Moon, Jamie O. Edgin et al. · Child Development · 2003 · 517 citations

, , +17