A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

Tao Yu, Zhongyou Li, Zhengping Jia, +18

Human Molecular Genetics

GeneticsMolecular GeneticsEpigeneticsHsa21 GenesMouse Model +14

Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice

Tao Yu, Chunhong Liu, Pavel V. Belichenko, +16

Brain Research

Individual Segmental TrisomiesNeuropsychologyCognitive ScienceBrain FunctionDevelopmental Cognitive Neuroscience +9

Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1)

Suhail Asrar, Yanghong Meng, Zikai Zhou, +3

Neuropharmacology

Molecular PhysiologySignal TransductionSignaling PathwayHippocampal Long-term PotentiationNeuroscience +6

Regulation of ADF/cofilin phosphorylation and synaptic function by LIM-kinase

Yanghong Meng, Hisaaki Takahashi, Jinsong Meng, +5

Neuropharmacology

Synaptic PlasticityMolecular NeuroscienceSignal TransductionSignaling PathwayAdf/cofilin Phosphorylation +6

p21-Activated Kinases 1 and 3 Control Brain Size through Coordinating Neuronal Complexity and Synaptic Properties

Wayne Huang, Zikai Zhou, Suhail Asrar, +3

Molecular and Cellular Biology

Developmental Cognitive NeuroscienceNeurotransmissionSynaptic PropertiesStructural PlasticitySocial Sciences +20

A critical role of Rho-kinase ROCK2 in the regulation of spine and synaptic function

Zikai Zhou, Yanghong Meng, Suhail Asrar, +2

Neuropharmacology

Synaptic PlasticityMolecular NeuroscienceMolecular PhysiologySignal TransductionSignaling Pathway +12

LIMK1 Regulates Long-Term Memory and Synaptic Plasticity via the Transcriptional Factor CREB

Zarko Todorovski, Suhail Asrar, Jackie Liu, +6

Molecular and Cellular Biology

Limk1 GeneDevelopmental Cognitive NeuroscienceSynaptic TransmissionStructural PlasticitySocial Sciences +16

Ca2+ Permeable AMPA Receptor Induced Long-Term Potentiation Requires PI3/MAP Kinases but Not Ca/CaM-Dependent Kinase II

Suhail Asrar, Zikai Zhou, Wei Ren, +1

PLoS ONE

Help from above: outer space and the fight against Ebola

Farhan M. Asrar, Suhail Asrar, J. B. Clark, +5

The Lancet Infectious Diseases

Outer SpaceEmerging Infectious DiseasesGlobal HealthSpace PolicyDisease Outbreak +2