Diastereoselective nickel-catalyzed reductive couplings of aminoaldehydes and alkynylsilanes: application to the synthesis of d-erythro-sphingosine

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

Yusuf A. Hannun, Carson R. Loomis, Alfred H. Merrill et al. · Journal of Biological Chemistry · 1986 · 1.2K citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

The synthesis and configurational stability of differentially protected .beta.-hydroxy-.alpha.-amino aldehydes

Philip Garner, Jung Min Park · The Journal of Organic Chemistry · 1987 · 404 citations

Natural Sciences, Biochemistry, Chemistry +10

Catalytic Asymmetric Reductive Coupling of Alkynes and Aldehydes:  Enantioselective Synthesis of Allylic Alcohols and α-Hydroxy Ketones

Karen M. Miller, Wei‐Sheng Huang, Timothy F. Jamison · Journal of the American Chemical Society · 2003 · 296 citations

Natural Sciences, Chemistry, Catalysis +9

A New Stereoselective Method for the Preparation of Allylic Alcohols

Eric Oblinger, John Montgomery · Journal of the American Chemical Society · 1997 · 269 citations

Natural Sciences, Chemistry, Analytical Chemistry +4

Enantioselective Reductive Coupling of 1,3-Enynes to Heterocyclic Aromatic Aldehydes and Ketones via Rhodium-Catalyzed Asymmetric Hydrogenation:  Mechanistic Insight into the Role of Brønsted Acid Additives

Venukrishnan Komanduri, Michael J. Krische · Journal of the American Chemical Society · 2006 · 268 citations

Natural Sciences, Chemistry, Catalysis +15