Mutation screening in the<i>IRF6</i>‐gene in patients with apparently nonsyndromic orofacial clefts and a positive family history suggestive of autosomal‐dominant inheritance

Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes

Shinji Kondo, Brian C. Schutte, Rebecca J. Richardson et al. · Nature Genetics · 2002 · 901 citations · Full text

Life Sciences, Genetics, Molecular Genetics +5

Interferon Regulatory Factor 6 ( <i>IRF6</i> ) Gene Variants and the Risk of Isolated Cleft Lip or Palate

Theresa M. Zucchero, Margaret E. Cooper, Brion S. Maher et al. · New England Journal of Medicine · 2004 · 583 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Strong Evidence of Linkage Disequilibrium between Polymorphisms at the IRF6 Locus and Nonsyndromic Cleft Lip With or Without Cleft Palate, in an Italian Population

Luca Scapoli, Annalisa Palmieri, Marcella Martinelli et al. · The American Journal of Human Genetics · 2004 · 162 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Variation in IRF6 contributes to nonsyndromic cleft lip and palate

Susan H. Blanton, Amy Cortez, Samuel Stal et al. · American Journal of Medical Genetics Part A · 2005 · 136 citations · Full text

Dentistry, Genetics, Molecular Genetics +17

Association between IRF6 and nonsyndromic cleft lip with or without cleft palate in four populations

Ji Wan Park, Iain McIntosh, Jacqueline B. Hetmanski et al. · Genetics in Medicine · 2007 · 126 citations · Full text

Dentistry, Craniofacial Biology, Orthodontics +11