Concepedia

Challenges in biotechnology production—generic processes and process optimization for monoclonal antibodies

Sven D. Sommerfeld, Jochen Strube

Chemical Engineering and Processing - Process Intensification · 2005 · 182 citations · 10 references

DOI

Concepts

References

10

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations

, , +11

CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUM

Richard G. Ham · Proceedings of the National Academy of Sciences · 1965 · 840 citations · Full text

, , +17

Protein purification: Principles and practice

William B. Jakoby · Analytical Biochemistry · 1983 · 420 citations

, , +12

Biopharmaceutical benchmarks

Gary Walsh · Nature Biotechnology · 2000 · 204 citations

Clonal growth of Chinese hamster cell lines in protein-free media

W G Hamilton, Richard G. Ham · In Vitro Cellular & Developmental Biology - Plant · 1977 · 132 citations

, , +14