Pharmacological profile of DA-6886, a novel 5-HT4 receptor agonist to accelerate colonic motor activity in mice

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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S. Müller‐Lissner, I. Fumagalli, Karna Dev Bardhan et al. · Alimentary Pharmacology & Therapeutics · 2001 · 464 citations · Full text

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5-Hydroxytryptamine4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine

John R. Grider, Amy E. Foxx–Orenstein, Ji‐Guang Jin · Gastroenterology · 1998 · 348 citations · Full text

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Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation – a 12‐week, randomized, double‐blind, placebo‐controlled study

Eamonn M.M. Quigley, Lieve Vandeplassche, René Kerstens et al. · Alimentary Pharmacology & Therapeutics · 2008 · 345 citations

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Activation of Colonic Mucosal 5-HT4 Receptors Accelerates Propulsive Motility and Inhibits Visceral Hypersensitivity

Jill M. Hoffman, Karl R. Tyler, Sarah J. MacEachern et al. · Gastroenterology · 2012 · 267 citations · Full text

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