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The nitroreductase enzyme in walker cells that activates 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) to 5-(aziridin-1-YL)-4-hydroxylamino-2-nitrobenzamide is a form of NAD(P)H dehydrogenase (quinone) (EC 1.6.99.2)

Cellular EnzymologyBiochemistryReactive Nitrogen SpecieMedicineNatural SciencesCb 1954Walker CellsNitroreductase EnzymeChemical BiologyPharmacologyRedox BiologyNitrosative Stress