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Pharmacokinetic Modeling to Assess Factors Affecting the Oral Bioavailability of the Lactone and Carboxylate Forms of the Lipophilic Camptothecin Analogue AR-67 in Rats

Oral BioavailabilityAssess Factors AffectingPharmacokinetic ModelingBiochemistryPharmacological StudyMedicineExperimental PharmacologyPharmacotherapyPharmacologyPhysiologically-based Pharmacokinetic ModelingPharmacokineticsPharmacodynamic ModelingDrug Resistance