Differential glycosylation of polyclonal IgG, IgG-Fc and IgG-Fab isolated from the sera of patients with ANCA-associated systemic vasculitis

Lack of Fucose on Human IgG1 N-Linked Oligosaccharide Improves Binding to Human FcγRIII and Antibody-dependent Cellular Toxicity

Robert L. Shields, Jadine Lai, Rodney G. Keck et al. · Journal of Biological Chemistry · 2002 · 1.8K citations · Full text

Life Sciences, Biochemistry, Immunology +16

The Absence of Fucose but Not the Presence of Galactose or Bisecting N-Acetylglucosamine of Human IgG1 Complex-type Oligosaccharides Shows the Critical Role of Enhancing Antibody-dependent Cellular Cytotoxicity

Toyohide Shinkawa, Kazuyasu Nakamura, Naoko Yamane et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

Life Sciences, Biochemistry, Immunology +17

Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG

R. B. Parekh, R A Dwek, Brian J. Sutton et al. · Nature · 1985 · 1.2K citations

Medicine, Immunology, Internal Medicine +16

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

Pablo Umaña, Joël Joan Pierre Jean-Mairet, Radmila Moudry et al. · Nature Biotechnology · 1999 · 760 citations

Medicine, Cancer Biology, Oncology +16

Species-specific variation in glycosylation of IgG: evidence for the species-specific sialylation and branch-specific galactosylation and importance for engineering recombinant glycoprotein therapeutics

T. Shantha Raju, John B. Briggs, Sarah Borge et al. · Glycobiology · 2000 · 455 citations

Life Sciences, Biochemistry, Molecular Biology +17