Positive and Negative Transcriptional Regulation of the Foxp3 Gene is Mediated by Access and Binding of the Smad3 Protein to Enhancer I

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism

Janine L. Coombes, Karima R.R. Siddiqui, Carolina V. Arancibia-Cárcamo et al. · The Journal of Experimental Medicine · 2007 · 2.6K citations · Full text

Reciprocal T _H 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid

Daniel Mucida, Yunji Park, Gisen Kim et al. · Science · 2007 · 1.9K citations

TGFβ signals through a heteromeric protein kinase receptor complex

Jeffrey L. Wrana, Liliana Attisano, Juan M. Cárcamo et al. · Cell · 1992 · 1.5K citations

Signal Transduction, Molecular Physiology, Signaling Pathway +5

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

Ye Zheng, Steven Z. Josefowicz, Ashutosh Chaudhry et al. · Nature · 2010 · 1.1K citations · Full text

Chromatin, Transcriptional Regulation, Genetics +13

Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

Yukiko Tone, Keiji Furuuchi, Yoshitsugu Kojima et al. · Nature Immunology · 2007 · 777 citations

Transcriptional Regulation, Signal Transduction, Molecular Physiology +11