Bile acid metabolites control TH17 and Treg cell differentiation

Saiyu Hang, Donggi Paik, Lina Yao, +15

Nature

Treg Cell DifferentiationSignal TransductionBiliary TractT-regulatory CellBiliary Disorder +3

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

Ye Zheng, Steven Z. Josefowicz, Ashutosh Chaudhry, +3

Nature

ChromatinTranscriptional RegulationGeneticsT-regulatory CellTranscription Regulation +11

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

Ye Zheng, Ashutosh Chaudhry, Arnold Kas, +7

Nature

Transcriptional RegulationSignal TransductionT-regulatory CellImmunologyGene Regulation +11

An essential role for the IL-2 receptor in Treg cell function

Takatoshi Chinen, Arun Kannan, Andrew G. Levine, +7

Nature Immunology

InflammationCytokineSignal TransductionAutoimmune DiseaseTreg Cell Function +12

Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells

Ye Zheng, Steven Z. Josefowicz, Arnold Kas, +3

Nature

Foxp3 Target GenesLymphocyte DevelopmentGeneticsT-regulatory CellGene Regulation +6

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

Steven Z. Josefowicz, Rachel Niec, Hye Young Kim, +5

Nature

InflammationAutoimmune DiseaseT-regulatory CellImmunologyRegulatory T Cells +3

An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

Chyi‐Song Hsieh, Ye Zheng, Yuqiong Liang, +2

Nature Immunology

Autoimmune DiseaseAdaptive Immune SystemMedicineT-regulatory CellImmunology +8

An Essential Role of the NF-κB<i>/</i>Toll-Like Receptor Pathway in Induction of Inflammatory and Tissue-Repair Gene Expression by Necrotic Cells

Ming O. Li, David F. Carpio, Ye Zheng, +5

The Journal of Immunology

Dendritic Cell Development and Survival Require Distinct NF-κB Subunits

F Ouaaz, Joseph R. Arron, Ye Zheng, +2

Immunity

InflammationDendritic Cell DevelopmentImmune Cell DevelopmentInnate Immune SystemImmunology +10

Depletion of fat-resident Treg cells prevents age-associated insulin resistance

Sagar P. Bapat, Jae Myoung Suh, Sungsoon Fang, +11

Nature

ObesityMetabolic SyndromeFat-resident Treg CellsLongevityDiabetes +6