Delayed effect of administration of COX-2 inhibitor in mice with acute cerebral ischemia

Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats.

Teng‐Nan Lin, Yang He, Gang Wu et al. · Stroke · 1993 · 722 citations · Full text

Medicine, Neurobiology, Neuroscience +14

Cyclo-Oxygenase-2 Gene Expression in Neurons Contributes to Ischemic Brain Damage

Shigeru Nogawa, Fangyi Zhang, M. Elizabeth Ross et al. · Journal of Neuroscience · 1997 · 721 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through <i>N</i> -methyl- <scp>d</scp> -aspartic acid-receptors and phospholipase A ₂

Susanna Miettinen, Francesca R. Fusco, Juha Yrjänheikki et al. · Proceedings of the National Academy of Sciences · 1997 · 287 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Cyclooxygenase‐2 is induced globally in infarcted human brain

Tiina Sairanen, Ari Ristimäki, Marja‐Liisa Karjalainen‐Lindsberg et al. · Annals of Neurology · 1998 · 192 citations

Medicine, Neurobiology, Neuroscience +15

The Cyclooxygenase-2 Inhibitor NS-398 Ameliorates Ischemic Brain Injury in Wild-Type Mice but not in Mice with Deletion of the Inducible Nitric Oxide Synthase Gene

Masao Nagayama, Kiyoshi Niwa, Tomiko Nagayama et al. · Journal of Cerebral Blood Flow & Metabolism · 1999 · 130 citations

Medicine, Neuroscience, Pharmacology +17