Relaxin requires the angiotensin II type 2 receptor to abrogate renal interstitial fibrosis

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

John R. Teerlink, Gad Cotter, Beth A. Davison et al. · The Lancet · 2012 · 908 citations

Medicine, Cardiology, Pharmacology +11

Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice

Lutz Hein, Gregory S. Barsh, Richard E. Pratt et al. · Nature · 1995 · 743 citations

Medicine, Genetics, Pharmacology +13

The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer.

Masatoshi Nakajima, Howard G. Hutchinson, Masahiko Fujinaga et al. · Proceedings of the National Academy of Sciences · 1995 · 679 citations

Life Sciences, Developmental Biology, Molecular Biology +17

The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats.

Helmy M. Siragy, Robert M. Carey · Journal of Clinical Investigation · 1997 · 483 citations · Full text

Medicine, Pharmacology, Physiology +16

Quantitative Assessment of β1- and β2-Adrenergic Receptor Homo- and Heterodimerization by Bioluminescence Resonance Energy Transfer

Jean‐François Mercier, Ali Salahpour, Stéphane Angers et al. · Journal of Biological Chemistry · 2002 · 470 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14