PLoS Biology · 2015 · 187 citations · 52 references
Life SciencesDevelopmental BiologyNeuroscienceDevelopmental NeurobiologyDevelopmental NeuroscienceNeuroplasticityBrain DevelopmentNeural DevelopmentNeural DifferentiationNeural PlasticityNeural Stem CellsNeurogenesisAdult Brain PlasticityAdult NeuroplasticityAdult PlasticityComparative Neural PlasticityDevelopmental NeurogenesisEmbryonic NeurogenesisNeural ProliferationRodent Neurogenesis
New neurons are continuously generated in specific regions in the adult brain. Studies in rodents have demonstrated that adult-born neurons have specific functional features and mediate neural plasticity. Data on the extent and dynamics of adult neurogenesis in adult humans are starting to emerge, and there are clear similarities and differences compared to other mammals. Why do these differences arise? And what do they mean?
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