Concepedia

Targeted Disruption of TGF-β/Smad3 Signaling Modulates Skin Fibrosis in a Mouse Model of Scleroderma

Gabriella Lakos, Shinsuke Takagawa, Shu-Jen Chen, Ahalia M. Ferreira, Gangwen Han, Koichi Masuda, Xiao‐Jing Wang, Luisa A. DiPietro, John Varga

American Journal Of Pathology · 2004 · 213 citations · 57 references

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57

Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene

Sylviane Dennler · The EMBO Journal · 1998 · 1.8K citations · Full text

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Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation

Peter A. Kavsak, Richele K. Rasmussen, Carrie G. Causing et al. · Molecular Cell · 2000 · 1.3K citations · Full text

, , +12

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

Sharon M. Wahl, D A Hunt, Lalage M. Wakefield et al. · Proceedings of the National Academy of Sciences · 1987 · 1.3K citations · Full text

, , +17

Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

Gillian S. Ashcroft, Xiao Yang, Adam B. Glick et al. · Nature Cell Biology · 1999 · 912 citations

, , +13

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF‐β

Xiao Yang · The EMBO Journal · 1999 · 902 citations

, , +16