Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Gökhan S. Hotamışlıgil, Narinder S. Shargill, Bruce M. Spiegelman · Science · 1993 · 7.5K citations

Medicine, Endocrinology, Molecular Biology +17

Biologic basis for interleukin-1 in disease

CA Dinarello · Blood · 1996 · 4.4K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.

Peter Arner, J F, Richard L. Atkinson et al. · Journal of Clinical Investigation · 1995 · 3.5K citations · Full text

Life Sciences, Molecular Biology, Physiology +16

C-Reactive Protein in Healthy Subjects: Associations With Obesity, Insulin Resistance, and Endothelial Dysfunction

John Yudkin, Coen D.A. Stehouwer, J.J. Emeis et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1999 · 2.5K citations · Full text

Veterinary Medicine, Endocrinology, Immunology +17