Simvastatin Ameliorates Angiotensin II-Induced Endothelial Dysfunction Through Restoration of Rho-BH4-eNOS-NO Pathway

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

Ulf Landmesser, Sergey Dikalov, S. Russ Price et al. · Journal of Clinical Investigation · 2003 · 1.5K citations · Full text

Life Sciences, Biochemistry, Physiology +16

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

Ulf Landmesser, Sergey Dikalov, S. Russ Price et al. · Journal of Clinical Investigation · 2003 · 1.4K citations

Life Sciences, Biochemistry, Physiology +16

Rho GTPase/Rho Kinase Negatively Regulates Endothelial Nitric Oxide Synthase Phosphorylation through the Inhibition of Protein Kinase B/Akt in Human Endothelial Cells

Xiu‐Fen Ming, Hema Viswambharan, Christine Barandiér et al. · Molecular and Cellular Biology · 2002 · 403 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertension

Thomas Wallerath, Klaus K. Witte, Stephan Schäfer et al. · Proceedings of the National Academy of Sciences · 1999 · 288 citations

Medicine, Pharmacology, Physiology +13

Reversal of Cardiac Hypertrophy and Fibrosis From Pressure Overload by Tetrahydrobiopterin

An L. Moens, Eiki Takimoto, Carlo G. Tocchetti et al. · Circulation · 2008 · 234 citations · Full text

Life Sciences, Pharmacology, Physiology +16