Rho GTPase/Rho Kinase Negatively Regulates Endothelial Nitric Oxide Synthase Phosphorylation through the Inhibition of Protein Kinase B/Akt in Human Endothelial Cells

Xiu‐Fen Ming, Hema Viswambharan, Christine Barandiér, +4

Molecular and Cellular Biology

Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance

Baptiste Rode, Jian Shi, Naima Endesh, +22

Nature Communications

Thrombin Stimulates Human Endothelial Arginase Enzymatic Activity via RhoA/ROCK Pathway

Xiu‐Fen Ming, Christine Barandiér, Hema Viswambharan, +8

Circulation

Mutation of the Circadian Clock Gene <i>Per2</i> Alters Vascular Endothelial Function

Hema Viswambharan, João Miguel Carvas, Vladan Antic, +7

Circulation

Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis

Adil Rajwani, Vivienne Ezzat, Jessica Smith, +18

Diabetes

HypertensionIgfbp1 ConcentrationNitric OxideInsulin SignalingOxidative Stress +19

Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance–Related Endothelial Cell Dysfunction

Piruthivi Sukumar, Hema Viswambharan, Helen Imrie, +14

Diabetes

Superoxide GenerationRedox BiologyInsulin SignalingOxidative StressInflammation +19

Endothelial-Specific Deletion of Connexin40 Promotes Atherosclerosis by Increasing CD73-Dependent Leukocyte Adhesion

Christos Chadjichristos, K.E. Ludwig Scheckenbach, Toon A.B. van Veen, +15

Circulation

HMG-CoA reductase inhibition improves endothelial cell function and inhibits smooth muscle cell proliferation in human saphenous veins

Zhihong Yang, Toshiyoki Kozai, Bernd van de Loo, +5

Journal of the American College of Cardiology

AngiogenesisBiochemistryHuman Saphenous VeinsAtherosclerosisNatural Sciences +12

Reconstituted High-Density Lipoprotein Inhibits Thrombin-Induced Endothelial Tissue Factor Expression Through Inhibition of RhoA and Stimulation of Phosphatidylinositol 3-Kinase but not Akt/Endothelial Nitric Oxide Synthase

Hema Viswambharan, Xiu‐Fen Ming, Shengsi Zhu, +5

Circulation Research

Vascular DiseaseEndothelial CellsActive Pi3k MutantOxidative StressInflammation +15

The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium

Afroze Abbas, Helen Imrie, Hema Viswambharan, +14

Diabetes