Concepedia

Sulforaphane inhibits the engagement of LPS with TLR4/MD2 complex by preferential binding to Cys133 in MD2

Jung Eun Koo, Zee‐Yong Park, Nam Doo Kim, Joo Young Lee

Biochemical and Biophysical Research Communications · 2013 · 77 citations · 14 references

DOI

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References

14

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

Beom Seok Park, Dong Hyun Song, Ho Min Kim et al. · Nature · 2009 · 2.4K citations

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MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4

Rintaro Shimazu, Sachiko Akashi, Hirotaka Ogata et al. · The Journal of Experimental Medicine · 1999 · 2.2K citations · Full text

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Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran

Ho Min Kim, Beom Seok Park, Jung-In Kim et al. · Cell · 2007 · 1.2K citations · Full text

, , +12

Essential role of MD-2 in LPS responsiveness and TLR4 distribution

Yoshinori Nagai, Sachiko Akashi, Masakazu Nagafuku et al. · Nature Immunology · 2002 · 1K citations

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Nuclear Factor κB Is a Molecular Target for Sulforaphane-mediated Anti-inflammatory Mechanisms

Christian Herhaus, Karin Klimo, Helmut Bartsch et al. · Journal of Biological Chemistry · 2001 · 627 citations · Full text

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