Effects of the selective bisindolylmaleimide protein kinase C inhibitor GF 109203X on P-glycoprotein-mediated multidrug resistance

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 54.9K citations

Cellular Growth, Rapid Colorimetric Assay, Cytotoxicity Assays +11

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

Dominique Toullec, P. Pianetti, Hervé Coste et al. · Journal of Biological Chemistry · 1991 · 2.5K citations · Full text

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976

Georg Martiny‐Baron, Marcelo G. Kazanietz, Harald Mischak et al. · Journal of Biological Chemistry · 1993 · 1.6K citations · Full text

Isolation and genetic characterization of human KB cell lines resistant to multiple drugs

Shin‐ichi Akiyama, Antonio Tito Fojo, John A. Hanover et al. · Somatic Cell and Molecular Genetics · 1985 · 553 citations

Human Cell, Health Sciences, Cytogenetics +6

Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells.

Kazuyuki Yusa, T Tsuruo · PubMed · 1989 · 367 citations

Proteinlipid Interaction, P-glycoprotein Transports Verapamil, Cellular Pharmacology +25