Concepedia

CYP2C polymorphisms, phenytoin metabolism and gingival overgrowth in epileptic subjects

Yoshihiko Soga, Fusanori Nishimura, Yoko Ohtsuka, Hiroaki Araki, Yoshihiro Iwamoto, Hisa Naruishi, Nobuyuki Shiomi, Yoshitomo KOBAYASHI, Shogo Takashiba, Kenji Shimizu,

Life Sciences · 2003 · 74 citations · 15 references

DOI

Concepts

References

15

The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans.

S.M. de Morais, G. Wilkinson, Joyce Blaisdell et al. · Journal of Biological Chemistry · 1994 · 952 citations · Full text

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The role of the CFP2C9-Leu 359 allelic variant in the tolbutamide polymorphism

Theresa H. Sullivan-Klose, Burhan I. Ghanayem, Douglas A. Bell et al. · Pharmacogenetics · 1996 · 587 citations

, , +17

Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations

Kōichi Nakamura, Fumio Goto, Wayne A. Ray et al. · Clinical Pharmacology & Therapeutics · 1985 · 457 citations

, , +14

Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man

A. K�pfer, R Preisig · European Journal of Clinical Pharmacology · 1984 · 364 citations

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Evidence That CYP2C19 is the Major (S)-Mephenytoin 4'-Hydroxylase in Humans

Jorge Goldstein, M B Faletto, M Romkes-Sparks et al. · Biochemistry · 1994 · 363 citations

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