Tolerance of Atlantic salmon, Salmo salar L., and rainbow trout, Oncorhynchus mykiss (Walbaum), to emamectin benzoate, a new orally administered treatment for sea lice

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

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Medicine, Pharmacokinetics, Pharmacology +14

The Mechanism of Action of Avermectins in Caenorhabditis Elegans: Correlation between Activation of Glutamate-Sensitive Chloride Current, Membrane Binding, and Biological Activity

Joseph P. Arena, Ken K. Liu, Philip S. Paress et al. · Journal of Parasitology · 1995 · 235 citations · Full text

Life Sciences, Pharmacology, Electrophysiology +10

P-Glycoprotein Deficiency in a Subpopulation of CF-1 Mice Enhances Avermectin-Induced Neurotoxicity

George R. Lankas, Mark E. Cartwright, Diane R. Umbenhauer · Toxicology and Applied Pharmacology · 1997 · 207 citations

Medicine, Neuroscience, Pharmacology +9

The efficacy of emamectin benzoate as an oral treatment of sea lice, <i>Lepeophtheirus salmonis</i> (KrÒyer), infestations in Atlantic salmon, <i>Salmo salar</i> L.

J Stone, I. H. Sutherland, C. Sommerville et al. · Journal of Fish Diseases · 1999 · 112 citations

Natural Resources, Fisheries, Veterinary Pharmacology +14

Evolutionary Relationship of the Ligand-Gated Ion Channels and the Avermectin-Sensitive, Glutamate-Gated Chloride Channels

Demetrios K. Vassilatis, Keith Elliston, Philip S. Paress et al. · Journal of Molecular Evolution · 1997 · 91 citations

Natural Sciences, Evolutionary Biology, Neuroscience +16