Effective long-term immunosuppression in rats by subcutaneously implanted sustained-release tacrolimus pellet: Effect on spinally grafted human neural precursor survival

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics.

Toru Kino, Hiroshi Hatanaka, MICHISANE HASHIMOTO et al. · The Journal of Antibiotics · 1987 · 1.2K citations · Full text

Medicine, Biochemistry, Pharmacology +10

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

Karl Johe, Thomas G. Hazel, Thomas Müller et al. · Genes & Development · 1996 · 1.2K citations · Full text

Life Sciences, Developmental Biology, Neuroscience +15

A COMPARISON OF TACROLIMUS (FK506) AND CYCLOSPORINE FOR IMMUNOSUPPRESSION AFTER CADAVERIC RENAL TRANSPLANTATION1

John D. Pirsch, Joshua Miller, Mark H. Deierhoi et al. · Transplantation · 1997 · 1.1K citations

Medicine, Immunology, Nephrology +14

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

John J. Siekierka, Shirley H.Y. Hung, Martin Poe et al. · Nature · 1989 · 1K citations

Life Sciences, Biochemistry, Pharmacology +9

Histological evidence of fetal pig neural cell survival after transplantation into a patient with Parkinson's disease

Terrence W. Deacon, James M. Schumacher, Jonathan Dinsmore et al. · Nature Medicine · 1997 · 467 citations

Life Sciences, Neurobiology, Neuroscience +14