Molecular adjuvant HMGB1 enhances anti-influenza immunity during DNA vaccination

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

Devon J. Shedlock, Hao Shen · Science · 2003 · 1.4K citations

Cd4 Help, Adaptive Immune System, Neurovirology +14

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

Joseph C. Sun, Michael J. Bevan · Science · 2003 · 1.2K citations · Full text

Inflammation, Cd4 Help, Autoimmune Disease +15

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

Ken J. Ishii, Tatsukata Kawagoe, Shohei Koyama et al. · Nature · 2008 · 615 citations

Systems Biology, Signal Transduction, Adaptive Immune Responses +12

NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1

Claudia Semino, Giovanna Angelini, Alessandro Poggi et al. · Blood · 2005 · 325 citations · Full text

Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes

Jong J. Kirn, Mark L. Bagarazzi, Neil N. Trivedi et al. · Nature Biotechnology · 1997 · 221 citations

Immunogenetics, Natural Sciences, Immunology +11