Getting the iron out: Phlebotomy for Alzheimer’s disease?

Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain <i>in vivo</i>

Wesley Farris, Stefan Mansourian, Yang Chang et al. · Proceedings of the National Academy of Sciences · 2003 · 1.5K citations · Full text

Life Sciences, Genetics, Neuroscience +15

Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study

Albert Hofman, Alewijn Ott, Monique M.B. Breteler et al. · The Lancet · 1997 · 1.4K citations

Medicine, Geriatric Medicine, Neurology +12

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

Mark A. Smith, Peggy L.R. Harris, Lawrence M. Sayre et al. · Proceedings of the National Academy of Sciences · 1997 · 1.4K citations

Life Sciences, Neurobiology, Neuroscience +17

Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease

Gorazd B. Stokin, Concepción Lillo, Tomás L. Falzone et al. · Science · 2005 · 1.2K citations

Life Sciences, Neurobiology, Neuroscience +17

IRON AND THE SEX DIFFERENCE IN HEART DISEASE RISK

JeromeL. Sullivan · The Lancet · 1981 · 979 citations

Medicine, Cardiology, Nutritional Sciences +10