Disease–drug interaction: Reduced response to propranolol despite increased concentration in the rat with inflammation

Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte beta-adrenergic responsiveness.

T Gulick, Mina K. Chung, Stephen J. Pieper et al. · Proceedings of the National Academy of Sciences · 1989 · 497 citations · Full text

Life Sciences, Immunology, Physiology +17

Regulation of cytochrome p450 by inflammatory mediators: why and how?

Edward T. Morgan · PubMed · 2001 · 359 citations

Medicine, Biochemistry, Pharmacology +17

Increased Plasma Protein Binding of Propranolol and Chlorpromazine Mediated by Disease-Induced Elevations of Plasma α₁Acid Glycoprotein

Kenneth M. Piafsky, Ingegerd Odar‐Cederlöf, C. Johansson et al. · New England Journal of Medicine · 1978 · 293 citations

Medicine, Clinical Pharmacokinetics, Pharmacology +15

Serum C-reactive protein concentration in acute myocardial infarction and its relationship to mortality during 24 months of follow-up in patients under thrombolytic treatment

K. O. Pietlla, Aimo Harmoinen, J. Jokiniitty et al. · European Heart Journal · 1996 · 263 citations · Full text

Medicine, Cardiology, Clinical Biochemistry +16

CAUSE OF DEATH IN RHEUMATOID ARTHRITIS

P Prior, Deborah Symmons, David L. Scott et al. · Lara D. Veeken · 1984 · 248 citations

Medicine, Infectious Diseases, Clinical Epidemiology +12