BACE inhibitor reduces APP-β-C-terminal fragment accumulation in axonal swellings of okadaic acid-induced neurodegeneration

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Jie Kang, Hans-Georg Lemaire, Axel Unterbeck et al. · Nature · 1987 · 4.6K citations

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Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

Paulina V. Arriagada, John H. Growdon, E. Tessa Hedley‐Whyte et al. · Neurology · 1992 · 2.7K citations

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

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Neurodegenerative Diseases, Molecular Neuroscience, Alzheimer's Disease +12

Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease

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