The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells

Nucleophosmin/B23 Is a Target of CDK2/Cyclin E in Centrosome Duplication

Masaru Okuda, Henning F. Horn, Pheruza Tarapore et al. · Cell · 2000 · 672 citations · Full text

Chromatin, Protein Function, Cell Division +9

Nucleophosmin regulates the stability and transcriptional activity of p53

Emanuela Colombo, Jean‐Christophe Marine, Davide Danovi et al. · Nature Cell Biology · 2002 · 536 citations

Molecular Regulation, Cell Death, Transcriptional Activity +2

Hsp70 Inhibits Heat-induced Apoptosis Upstream of Mitochondria by Preventing Bax Translocation

Adam R. Stankiewicz, Guillaume Lachapelle, Cheryl P.Z. Foo et al. · Journal of Biological Chemistry · 2005 · 423 citations · Full text

Mitochondrial Disruption, Signal Transduction, Biochemistry +13

Prohibitin Induces the Transcriptional Activity of p53 and Is Exported from the Nucleus upon Apoptotic Signaling

Gina Fusaro, Piyali Dasgupta, S. Rastogi et al. · Journal of Biological Chemistry · 2003 · 353 citations · Full text

Is Exported, Molecular Biology, Cell Death +16

Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines

Shinichi Ikemoto, Kazunobu Sugimura, Naomasa Yoshida et al. · Urology · 2000 · 285 citations

Oncology, Chemoprevention Strategy, Medicine +8