IL-18 Inhibits TNF-α-Induced Osteoclastogenesis Possibly via a T Cell-Independent Mechanism in Synergy with IL-12 In Vivo

Cloning of a new cytokine that induces IFN-γ production by T cells

Haruki Okamura, Hiroko Tsutsui, Toshinori Komatsu et al. · Nature · 1995 · 2.6K citations

Life Sciences, Biotechnology, Immunology +16

Tumor Necrosis Factor α Stimulates Osteoclast Differentiation by a Mechanism Independent of the Odf/Rankl–Rank Interaction

Kanichiro Kobayashi, Naoyuki Takahashi, Eijiro Jimi et al. · The Journal of Experimental Medicine · 2000 · 1.3K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Murine Macrophages Secrete Interferon γ upon Combined Stimulation with Interleukin (IL)-12 and IL-18: A Novel Pathway of Autocrine Macrophage Activation

Markus Munder, Moisés Mallo, Klaus Eichmann et al. · The Journal of Experimental Medicine · 1998 · 598 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Interleukin-18 (Interferon-γ–inducing Factor) Is Produced by Osteoblasts and Acts Via Granulocyte/Macrophage Colony-stimulating Factor and Not Via Interferon-γ to Inhibit Osteoclast Formation

Nobuyuki Udagawa, Nicole J. Horwood, Jan Elliott et al. · The Journal of Experimental Medicine · 1997 · 376 citations · Full text

Medicine, Cell Biology, Immunology +12

Osteoclast differentiation independent of the TRANCE–RANK–TRAF6 axis

Nacksung Kim, Yuho Kadono, Masamichi Takami et al. · The Journal of Experimental Medicine · 2005 · 371 citations · Full text

Life Sciences, Cell Biology, Immunology +17