Gene transfer efficiency of high primary amine content, hydrophobic, alkyl-oligoamine derivatives of polyethylenimine

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations · Full text

Engineering, In Vivo Gene Therapy, Several Polycations +20

Gene therapy - promises, problems and prospects

Inder M. Verma, Nikunj V. Somia · Nature · 1997 · 1.7K citations · Full text

Gene Therapies, Novel Therapy, Genetic Engineering +5

An improved 2,4,6-trinitrobenzenesulfonic acid method for the determination of amines

Stephen L. Snyder, P. Z. Sobocinski · Analytical Biochemistry · 1975 · 753 citations

Chemical Engineering, Chemical Measurement, Engineering +7

Virus treatment questioned after gene therapy death

Sally Lehrman · Nature · 1999 · 576 citations · Full text

Gene Therapies, Viral Persistence, Virus Treatment +4

Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer.

Robert E. Donahue, Steven Kessler, David M. Bodine et al. · The Journal of Experimental Medicine · 1992 · 537 citations · Full text

Viral Replication, Cell Therapy, Immunology +16