Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology

Clinical diagnosis of Alzheimer's disease

Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 28K citations · Full text

Medicine, Geriatric Medicine, Neurology +16

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Karen Hsiao, Paul F. Chapman, Steven P. Nilsen et al. · Science · 1996 · 4.2K citations

Life Sciences, Neurobiology, Neuroscience +17

Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)

Takeshi Iwatsubo, Asano Odaka, Nobuhiro Suzuki et al. · Neuron · 1994 · 1.8K citations

Life Sciences, Neuroscience, Pathology +16

Age-Dependent Changes in Brain, CSF, and Plasma Amyloid β Protein in the Tg2576 Transgenic Mouse Model of Alzheimer's Disease

Takeshi Kawarabayashi, Linda H. Younkin, Takaomi C. Saido et al. · Journal of Neuroscience · 2001 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

J. Steven Jacobsen, Chi-Cheng Wu, Jeffrey M. Redwine et al. · Proceedings of the National Academy of Sciences · 2006 · 708 citations · Full text

Life Sciences, Neurology, Neuroscience +17