Critical Care Medicine · 2008 · 58 citations · 37 references
CSF levels of HMGB1 and Hsp72 were significantly higher in patients with bacterial meningitis than those with aseptic meningitis and correlated well with CSF white blood cell counts in patients with bacterial (but not aseptic) meningitis.
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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
Paola Scaffidi, Tom Misteli, Marco E. Bianchi · Nature · 2002 · 4.1K citations
Inflammation, Chromatin, Cytokine +10
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Haichao Wang, Ona Bloom, Minghuang Zhang et al. · Science · 1999 · 3.4K citations