Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells

Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.

John P. Iredale, R. Christopher Benyon, J. Pickering et al. · Journal of Clinical Investigation · 1998 · 1.1K citations · Full text

Medicine, Cell Biology, Pathology +17

Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes

Kazuyoshi Kon, Jae‐Sung Kim, Hartmut Jaeschke et al. · Hepatology · 2004 · 494 citations · Full text

Veterinary Medicine, Cell Biology, Pharmacology +17

The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances

Norifumi Kawada, Thuy‐Anh Tran‐Thi, Heike KLEIN et al. · European Journal of Biochemistry · 1993 · 392 citations · Full text

Life Sciences, Cell Biology, Physiology +13

Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats

Matthew C. Wright, Razo Issa, David E. Smart et al. · Gastroenterology · 2001 · 355 citations · Full text

Life Sciences, Cell Biology, Pathology +14

Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis

Fiona Oakley, Muriel Meso, John P. Iredale et al. · Gastroenterology · 2005 · 265 citations · Full text

Medicine, Cell Biology, Pathology +17