Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis

Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.

John P. Iredale, R. Christopher Benyon, J. Pickering et al. · Journal of Clinical Investigation · 1998 · 1.1K citations · Full text

Medicine, Cell Biology, Pathology +17

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

Kui Lei, Roger J. Davis · Proceedings of the National Academy of Sciences · 2003 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536 in the Transactivation Domain

Hiroaki Sakurai, Hiroaki Chiba, Hidetaka Miyoshi et al. · Journal of Biological Chemistry · 1999 · 820 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13

Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B.

Claudia Wahl, Susanne Liptay, G. Adler et al. · Journal of Clinical Investigation · 1998 · 740 citations · Full text

Medicine, Immunology, Pharmacology +17

Selective Inhibition of NF-κB Activation by a Peptide That Blocks the Interaction of NEMO with the IκB Kinase Complex

Michael J. May, Fulvio D’Acquisto, Lisa A. Madge et al. · Science · 2000 · 681 citations

Medicine, Molecular Biology, Pharmacology +17