MicroRNA-101 mediates the suppressive effect of laminar shear stress on mTOR expression in vascular endothelial cells

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Brinda Ravikumar, Zdenek Berger, J. Eric Davies et al. · Nature Genetics · 2004 · 2.3K citations

Life Sciences, Genetics, Neuroscience +17

Laminar Shear Stress

Oren Traub, Bradford C. Berk · Arteriosclerosis Thrombosis and Vascular Biology · 1998 · 1.1K citations

Life Sciences, Cell Biology, Physiology +17

mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E

Diane C. Fingar, Celeste Richardson, Andrew R. Tee et al. · Molecular and Cellular Biology · 2003 · 873 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro

Yun Fang, Congzhu Shi, Elisabetta Manduchi et al. · Proceedings of the National Academy of Sciences · 2010 · 428 citations · Full text

Life Sciences, Immunology, Pathobiology +17

MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity

Martina Weber, Meredith B. Baker, Jeffrey P. Moore et al. · Biochemical and Biophysical Research Communications · 2010 · 383 citations

Life Sciences, Cell Biology, Molecular Biology +17