Concepedia

Comparison of Lentiviral and Adenoviral Gene Therapy for Spinal Fusion in Rats

Masashi Miyazaki, Osamu Sugiyama, Jun Zou, Seung Hwan Yoon, Feng Wei, Yuichiro Morishita, Chananit Sintuu, Mandeep S. Virk, Jay R. Lieberman, Jeffrey C. Wang

Spine · 2008 · 54 citations · 24 references

DOI

Abstract

BMP-2-producing RBMCs developed using lentiviral gene transfer induced more abundant bone within the fusion mass than the RBMCs transduced via adenoviral gene transfer and recombinant protein therapy.

References

24

Novel Regulators of Bone Formation: Molecular Clones and Activities

John M. Wozney, Vicki Rosen, Anthony Celeste et al. · Science · 1988 · 3.9K citations

A Third-Generation Lentivirus Vector with a Conditional Packaging System

Tom Dull, Romain Zufferey, Michael T. Kelly et al. · Journal of Virology · 1998 · 3.3K citations · Full text

, , +18

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

Romain Zufferey, Dea Nagy, Ron J. Mandel et al. · Nature Biotechnology · 1997 · 2K citations · Full text

, , +8

Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery

Romain Zufferey, Thomas J. Dull, Ronald J. Mandel et al. · Journal of Virology · 1998 · 1.8K citations · Full text

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.

Yang Yang, Frederick A. Nunes, Klára Berencsi et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations · Full text

, , +19