Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

Romain Zufferey, Dea Nagy, Ron J. Mandel, +2

Nature Biotechnology

Cell-based Drug DeliveryEngineeringIn Vivo Gene TherapyGenetic EngineeringVirology +6

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

Richard O. Snyder, Carol H. Miao, G. Patijn, +9

Nature Genetics

Hepatic Gene TransferHepatologyLiver PhysiologyImmunologyAntiviral Response +7

Antibody-Based Detection of ERG Rearrangement-Positive Prostate Cancer

Kyung Park, Scott A. Tomlins, Kumaran Mudaliar, +16

Neoplasia

Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy

Haiyan Jiang, Linda B. Couto, Susannah Patarroyo‐White, +10

Blood

Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs

Haiyan Jiang, David Lillicrap, Susannah Patarroyo‐White, +12

Blood

In Vivo Gene Transfer by Intravenous Administration of Stable Cationic Lipid/DNA Complex

Hans Hofland, Dea Nagy, Jing‐Jie Liu, +4

Pharmaceutical Research

Sustained phenotypic correction of canine hemophilia A using an adeno-associated viral vector

Ciaran D. Scallan, David Lillicrap, Haiyan Jiang, +13

Blood

Distribution of AAV-TK following Intracranial Convection-Enhanced Delivery into Rats

Janet Cunningham, Yoshitsugu Oiwa, Dea Nagy, +3

Cell Transplantation

Testing mutual exclusivity of ETS rearranged prostate cancer

Maria A. Svensson, Christopher J. Lafargue, Theresa Y. MacDonald, +13

Laboratory Investigation

UrologyOncologyInterfocal HeterogeneityTumor HeterogeneityMedicine +7

Phenotypic correction of a mouse model of hemophilia A using AAV2 vectors encoding the heavy and light chains of FVIII

Ciaran D. Scallan, Tongyao Liu, Amy E. Parker, +11

Blood